颅骨修补 |
颅骨修补术（Cranioplasty，CP）是神经外科比较普遍且简单的手术，是在多种病因下，行去骨瓣减压术
（Decompressive Craniectomy，DC）后，再次修复缺失颅骨的一个治疗过程。
颅骨修复时采用的修补材料需具有生物相容性、惰性、抗感染、易于获取，易于成形，安全且成本低等特点 。修补材料分为自身材料、同种异体材料、异种异体材料、生物合成材料等。
Cranioplasty (CP) is a relatively common and straightforward neurosurgical procedure. It involves repairing a missing part of the skull following a decompressive craniectomy (DC), which is performed for various medical reasons.
The materials used for cranioplasty need to possess certain characteristics: biocompatibility, inertness, resistance to infection, ease of acquisition, ease of shaping, safety, and low cost. These materials can be classified into several categories: autologous materials, allogeneic materials, xenogeneic materials, and synthetic materials.
The choice of repair material is determined based on a combination of factors including medical technology, the patient's financial situation, religious beliefs, and the preference of the operating surgeon. Autologous bone (the patient’s own bone) is generally the first choice for cranioplasty materials.
自体颅骨 |
与人工材料相比，自体颅骨无疑是修复材料的最佳选择。相对于钛网，自体颅骨能显著降低金属异物引发的 过敏和排异反应，最大程度减少术后并发症。同时，自体颅骨的材料费用较PEEK大幅降低。因此，如果能 妥善保存并经过适当处理，将自体颅骨应用于颅骨修复手术中将为医患双方提供最优解决方案。
通过专业机构保存，手术取出的颅骨在一年内能较好地保留自身活性，可用于自体颅骨修复。修复手术后，骨瓣可成功成活并良好融合周围骨质，具有良好的组织相容性，提高患者在心理层面的接受度，创造出更良好的就医体验。
自体颅骨修复技术的推广为医患双方在颅骨修复上提供更多元、全面的选择。选择最佳修复材料和治疗手段 有助于患者重新塑造完美头颅，提高生活质量。
Autologous Bone
Compared to artificial materials, autologous bone is undoubtedly the best choice for cranioplasty. Unlike titanium mesh, autologous bone significantly reduces the risk of allergic reactions and rejection caused by foreign metal objects, thereby minimizing postoperative complications. Additionally, the cost of autologous bone is substantially lower than that of PEEK (polyether ether ketone). Therefore, if properly preserved and adequately treated, using autologous bone in cranioplasty offers the optimal solution for both patients and healthcare providers.
When preserved by specialized institutions, the bone removed during surgery can retain its viability for up to a year and can be used effectively for autologous bone repair. Post-repair surgery, the bone flap can successfully integrate and fuse well with the surrounding bone, demonstrating excellent tissue compatibility. This enhances the patient's psychological acceptance and overall medical experience.
The promotion of autologous bone repair technology provides more diverse and comprehensive options for both patients and healthcare providers in cranioplasty. Selecting the best repair materials and treatment methods helps patients restore a perfect skull and improve their quality of life.
自体颅骨优势 |
1、减少手术操作步骤和时间
2、降低医疗成本
3、避免异体异种移植物之间的疾病传播
4、恢复正常颅骨的保温和散热功能，避免脑组织受温度变化影响
5、促进骨移植重塑和生长，无免疫排斥反应
6、头颅外形修复重建完美，无需修剪塑形
7、患者心理接受更佳，避免人工替代材料造成的心理负担
Advantages of Autologous Bone
1. **Reduces Surgical Steps and Time:** Using autologous bone simplifies the surgical procedure and shortens the operation time.
2. **Lowers Medical Costs:** The use of autologous bone significantly reduces overall medical expenses.
3. **Prevents Disease Transmission:** It avoids the risk of disease transmission associated with allogeneic or xenogeneic grafts.
4. **Restores Normal Skull Functions:** Autologous bone restores the natural insulating and heat dissipation functions of the skull, protecting brain tissue from temperature fluctuations.
5. **Promotes Bone Remodeling and Growth:** It supports natural bone remodeling and growth without the risk of immune rejection.
6. **Achieves Perfect Skull Reconstruction:** The use of autologous bone results in a more accurate and aesthetically pleasing skull reconstruction without the need for additional shaping.
7. **Enhances Psychological Acceptance:** Patients are more psychologically comfortable with autologous bone, avoiding the mental burden associated with artificial substitute materials.
病例 |
患者左侧颅骨缺损导致外观严重受损，同时由于再次头部碰撞可能引起颅内损伤的风险显著增加。神经外科 医生为患者进行自体颅骨修补手术，成功重塑了完整的头颅结构。患者术后顺利返回病房，手术取得了安全 而有效的结果。
### Case of Autologous Bone Repair
A patient suffered from severe cosmetic deformity due to a defect in the left side of the skull, which also significantly increased the risk of intracranial injury from any subsequent head trauma. A neurosurgeon performed an autologous bone cranioplasty for the patient, successfully reconstructing the complete skull structure. The patient was safely and effectively returned to the ward post-surgery, with the operation yielding successful and effective results.
颅骨保存不仅仅是简单的灭菌冰冻过程，而是需要通过一系列严密的技术手段进行精心处理。作为颅骨保存专业的一站式服务机构，我们致力于为未来的颅骨修补成型提供最完美的修复材料。
Skull Preservation
Skull preservation is not merely a simple process of sterilization and freezing; it requires meticulous handling through a series of rigorous technical procedures. As a professional one-stop service provider specializing in skull preservation, we are dedicated to providing the most perfect repair materials for future cranioplasty and reconstruction.
自体颅骨低温保存 |
手术中取出的颅骨骨瓣经过专业机构的严格处理，包括自体颅骨性保存、清洗、灭菌，以及在模拟体内环境中 进行低温冰冻储存处理。这些处理确保颅骨在修补手术中能够作为有效的修复材料使用。
Low-Temperature Preservation of Autologous Bone
The bone flap removed during surgery undergoes strict processing by a professional institution, including autologous bone preservation, cleaning, sterilization, and low-temperature freezing storage in an environment that simulates the conditions inside the body. These procedures ensure that the bone can be effectively used as a repair material in subsequent cranioplasty surgeries.
技术优势保障 |
⭕️GMP标准的加工处理环境
⭕️严格的无菌操作与质控流程
⭕️生物灭菌技术应用
⭕️先进成熟的技术团队
⭕️恒低温质控方案的实施
⭕️出库前进行菌检，确保质量标准
⭕️具备丰富的大样本量保存经验 经安全有效性验证的颅骨保存方法
Technical Advantages Assurance
- ⭕️ **GMP Standard Processing Environment:** Ensures the highest quality in manufacturing and handling.
- ⭕️ **Strict Sterile Procedures and Quality Control Processes:** Maintains sterility and consistency in processing.
- ⭕️ **Application of Biological Sterilization Techniques:** Utilizes advanced methods to eliminate potential contaminants.
- ⭕️ **Advanced and Experienced Technical Team:** Employs skilled professionals with extensive expertise.
- ⭕️ **Implementation of Constant Low-Temperature Quality Control:** Ensures the preserved bone remains viable and effective.
- ⭕️ **Microbial Testing Before Release:** Conducts thorough testing to meet quality standards before distribution.
- ⭕️ **Extensive Experience with Large Sample Preservation:** Demonstrates proven methods for safe and effective skull preservation validated by substantial experience.
自体颅骨处理及存储流程 |Autologous Bone Processing and Storage Procedure
指南共识 |"Guidelines Consensus"
